Beta carotene is relatively safe. There is some concern that high doses of beta-carotene can cause a slight increase in the risk of heart disease and cancer, especially in people who smoke cigarettes and who consume excessive alcohol.
Other side effects include diarrhea and a yellowish tinge to the skin, both of which subside then the intake of beta-carotene is lowered.
Pregnancy and breast-feeding: Not enough is known about the use of beta-carotene during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Smoking: In people who smoke, beta-carotene supplements might increase the risk of lung and prostate cancer. Don’t take beta-carotene supplements if you smoke.
History of asbestos exposure: In people who have been exposed to asbestos, beta-carotene supplements might increase the risk of cancer. Don’t take beta-carotene supplements if you have been exposed to asbestos.
Angioplasty, a heart procedure. There is some concern that when antioxidant vitamins, including beta-carotene, are used together they might have harmful effects after angioplasty. They can interfere with healing. Don’t use beta-carotene and other antioxidant vitamins before or after angioplasty without the recommendation of your healthcare provider.
Be cautious with this combination.
Medications used for lowering cholesterol (Statins)
Taking beta-carotene, selenium, vitamin C, and vitamin E together might decrease the effectiveness of some medications used for lowering cholesterol. It is not known if beta-carotene alone decreases the effectiveness of some medications used for lowering cholesterol.
Some medications used for lowering cholesterol include atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), and pravastatin (Pravachol).
Niacin
Taking beta-carotene along with vitamin E, vitamin C, and selenium might decrease some of the beneficial effects of niacin. Niacin can increase the good cholesterol. Taking beta-carotene along with these other vitamins might decrease the good cholesterol.