Research
The clinical efficacy of Adipromin for weight loss has been demonstrated in two randomized, double-blind, placebo-controlled clinical trials (RCTs), published in well-respected medical journals.‡
The exemplary second RCT of Adipromin—published in a top-tier medical journal—was conducted in healthy overweight subjects (n=140). The 16-week study compared the use of Adipromin in conjunction with an 1800 kcal/day diet and walking plan (30 min 5 times per week) to a placebo with the same diet and walking plan.
Dixit K, et al. Efficacy of a novel herbal formulation for weight loss demonstrated in a 16-week randomized, double-blind, placebo-controlled clinical trial with healthy overweight adults. Diabetes Obes Metab. 2018;20(11):2633-2641. doi:10.1111/dom.13443
- At the end of the study, subjects taking Adipromin showed significant reductions in body weight (-11.82 pounds vs. -1.92 pounds; p < 0.0001) and BMI (2.05 kg vs. 0.34 kg/m2; p < 0.0001), compared with placebo.‡
- Subjects taking Adipromin had significant reductions in waist circumference (-2.12 inches vs. -0.67 inches; p < 0.0001) and hip circumference (-1.77 inches vs. -0.47 inches p < 0.0001) compared with placebo.‡
- Subjects taking Adipromin had statistically significant improvement compared to placebo in their blood lipid profiles (p < 0.0001), including triglycerides.‡
- Subjects taking Adipromin had improved serum adiponectin (p = 0.0071) and serum ghrelin (p = 0.0568) compared to those taking placebo.‡
- Post-hoc analysis showed that subjects taking Adipromin had a more than 37% reduction in their Visceral Adiposity Index (VAI), whereas the VAI of those taking placebo increased slightly.
A third RCT, to be published in 2022, evaluated the impact of Adipromin on Resting Metabolic Rate (RMR) in healthy overweight subjects (n=60).4 By the end of the 7-day study, Adipromin supplementation had produced a significant increase in RMR compared to placebo (up to 15.2% higher), but with no stimulant effects, i.e., heart rate and blood pressure remained normal.* In fact, subjects felt better while burning more calories, as evidenced by a statistically significant improvement in their Profile of Mood States (POMS) scores compared to placebo.‡