OsteoBase provides targeted does of Magnesium, Vitamin K, Vitamin D and Calcium critical to maintaining Bone Health.
OsteoBase
includes 300 mg of elemental calcium and 300mg of elemental magnesium per
serving, with multiple forms of calcium to ensure maximum absorption. OsteoBase
also includes the highest-quality forms of vitamin K2 (MK-7), and vitamin D
(D3) to ensure maximum bioavailability and a synergistic benefit for the
absorption and assimilation of calcium within the body. OsteoBase covers the
most common nutrient deficiencies in one convenient, foundational bone
health
formula.
Benefits:
- Comprehensive Foundational Bone Health for All Ages
- Promotes Bone Health and Proper Calcium Storage
- Boosts Key Enzymes in Calcium Regulation
- Maintains Healthy Vitamin D Levels and Immune Health
Overview
Epidemiologic
studies and national nutrient surveys indicate key nutrient deficiencies are
widespread, specifically vitamin D, magnesium, and vitamin K. All play dynamic
roles in calcium absorption, integration and administration within the body.1-3
Current
research estimates that 70% of the US population doesn’t meet estimated average
requirements (EAR) for vitamin D; approximately 60% of the US population
doesn’t meet EAR for magnesium and approximately one-third of the western population
is deficient in vitamin K2.3,4 Poor diets, nutrient
depletion
from medications, and poor intestinal absorption all contribute to insufficient
intake of these foundational nutrients. OsteoBase provides 300 mg of calcium
(150 mg in the form of hydroxyapatite) and 300 mg of magnesium per serving, in a 1:1
ratio.
SIZE: 90 capsules
INGREDIENT BENEFITS
Hydroxyapatite
Calcium in bone is combined with phosphorus to
form microcrystalline hydroxyapatite (MCH). In the body, phosphorus is
second in abundance only to calcium, and is necessary for bone growth, cellular
health, and acid-alkaline balance. Phosphate makes up 50% of bone tissue and is
an essential ingredient in calcium supplements to promote bone strength and
remodeling. OsteoBase uses multiple forms of calcium, one being MCH, to
maximize absorption. Calcium is most well-known for its role in the formation
of bone and teeth, but it also plays a role in keeping the heart and muscles
functioning by governing muscle contractions.
Magnesium
Magnesium comprises about 1% of bone mineral and is known to
influence both bone matrix and bone mineral metabolism. A tight control of
magnesium homeostasis seems to be crucial for bone health. Magnesium plays a
major role in bone formation as approximately 50% of magnesium found in the
body is found in the bone. Magnesium plays numerous roles in bone health
including increasing calcium absorption, acting as a cofactor for alkaline
phosphatase activation, as well as supporting vitamin D3 conversion in the
body. As the magnesium content of bone mineral decreases, apatite crystals of
bone become larger and more brittle. In combination, magnesium malate enhances
the absorption of calcium, and works in tandem with calcium to allow muscles to
contract and relax. Combined, calcium and magnesium balance are maintained
through an intricately linked relationship that supports muscle, nervous system
function, and foundational bone health.
Vitamin K2 (as MK-7, MenaQ7®PRO)
Vitamin K2 helps to bind newly absorbed calcium to the mineral
matrix in bone through its activation of the protein osteocalcin. In addition,
vitamin K has been found to help maintain bone mineral density by decreasing
the activity of osteoclasts, or cells that break down the bone matrix. Vitamin
K also provides critical cardiovascular protection by helping to carboxylate
matrix GLA protein (MGP), an inhibitor of circulatory and soft tissue
calcification. A 2005 study from northern Finland found that those with greater
levels of vitamin K-carboxylated osteocalcin had stronger bones than those with
lower levels of the protein. A Japanese study found superior bone health among
women who frequently consumed vitamin K2 compared to those who did not.
Vitamin D (as D3)
Vitamin D is essential for the efficient utilization of calcium
by the body. Vitamin D normalizes serum calcium by increasing the intestinal
absorption of dietary calcium, increasing the reabsorption of calcium filtered
by the kidneys, and mobilizing calcium from bone when there is insufficient
dietary calcium to maintain normal serum calcium concentrations. Vitamin
K and vitamin D share similar qualities, and act in synergy within the body to
maintain calcium balance and proper distribution. A randomized study that split
172 women into a vitamin K2 group, a vitamin D3 group, a vitamin K2 and D3
group, and a placebo group for two years found that the combination of vitamin
D3 and K2 had the most benefits for supporting bone health among the groups.
This formulation includes 45 mcg of vitamin K2 and 1,000 IU of vitamin D3 per
capsule for optimal absorption and use by the body.
